Gene

strn3

ID

ZDB-GENE-030616-405

Name

striatin, calmodulin binding protein 3

Symbol

strn3 Nomenclature History

Previous Names

id:ibd1241
si:busm1-115o7.2
si:dz115o7.2
si:dz234g15.7
wu:fc02f06

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in negative regulation of intracellular estrogen receptor signaling pathway. Predicted to be located in cytoplasm. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in dendrite; neuronal cell body; and postsynapse. Is expressed in intertectal commissure; optic tectum; somite; and tail bud. Orthologous to human STRN3 (striatin 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Berger et al., 2022
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With strn3 Human Ortholog

No data available

Associated With strn3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR013258	Striatin, N-terminal
Family	IPR051488	WD repeat-containing striatin
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat