Gene
mc3r
- ID
- ZDB-GENE-030502-3
- Name
- melanocortin 3 receptor
- Symbol
- mc3r Nomenclature History
- Previous Names
-
- zgc:194235
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable melanocyte-stimulating hormone receptor activity and peptide hormone binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in brain; epiphysis; female organism; ovary; and testis. Human ortholog(s) of this gene implicated in obesity. Orthologous to human MC3R (melanocortin 3 receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Renquist et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Obesity, severe, susceptibility to, BMIQ9} | 602025 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Melanocortin 3 receptor | Melanocortin/ACTH receptor | Melanocortin receptor 3-5 |
|---|---|---|---|---|---|---|---|
| UniProtKB:F1QQG9 | InterPro | 327 |
Interactions and Pathways
No data available
Plasmids
No data available