Gene
nppa
- ID
- ZDB-GENE-030131-95
- Name
- natriuretic peptide A
- Symbol
- nppa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable hormone activity and hormone receptor binding activity. Acts upstream of or within atrioventricular canal development; cardiac jelly development; and cardiac muscle cell proliferation. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in heart rudiment; pericardial region; and skeletal muscle cell. Human ortholog(s) of this gene implicated in artery disease (multiple); heart conduction disease (multiple); and peritonitis. Orthologous to human NPPA (natriuretic peptide A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 142 figures from 103 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu811 (11 images)
- eu878 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| atrial standstill 2 | Alliance | Atrial standstill 2 | 615745 |
| familial atrial fibrillation | Alliance | Atrial fibrillation, familial, 6 | 612201 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Natriuretic peptide | Natriuretic peptide, conserved site | Natriuretic Peptide Hormone |
|---|---|---|---|---|---|
| UniProtKB:F1QVW0 | InterPro | 139 |
Interactions and Pathways
No data available
Plasmids
No data available