Gene
rplp1
- ID
- ZDB-GENE-030131-8663
- Name
- ribosomal protein lateral stalk subunit P1
- Symbol
- rplp1 Nomenclature History
- Previous Names
-
- fa93f02
- wu:fa93f02
- zgc:77776
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable protein kinase activator activity and ribonucleoprotein complex binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within erythrocyte differentiation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in unfertilized egg. Orthologous to human RPLP1 (ribosomal protein lateral stalk subunit P1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6906319 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Large ribosomal subunit protein P1/P2 | Large ribosomal subunit protein P1/P2, N-terminal domain |
|---|---|---|---|---|
| UniProtKB:Q6P5K5 | InterPro | 113 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-149A19 | ZFIN Curated Data | |
| Encodes | EST | fa93f02 | ||
| Encodes | EST | IMAGE:6906319 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:77776 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_200029 (1) | 520 nt | ||
| Genomic | GenBank:CU424444 (1) | 132828 nt | ||
| Polypeptide | UniProtKB:Q6P5K5 (1) | 113 aa |
- He, W.X., Wu, M., Liu, Z., Li, Z., Wang, Y., Zhou, J., Yu, P., Zhang, X.J., Zhou, L., Gui, J.F. (2018) Oocyte-specific maternal Slbp2 is required for replication-dependent histone storage and early nuclear cleavage in zebrafish oogenesis and embryogenesis. RNA (New York, N.Y.). 24(12):1738-1748
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Yadav, G.V., Chakraborty, A., Uechi, T., and Kenmochi, N. (2014) Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish. The international journal of biochemistry & cell biology. 49:1-7
- Carlson, P., Smalley, D.M., and Van Beneden, R.J. (2013) Proteomic analysis of arsenic-exposed zebrafish (Danio rerio) identifies altered expression in proteins involved in fibrosis and lipid uptake in a gender-specific manner. Toxicological sciences : an official journal of the Society of Toxicology. 134(1):83-91
- Zheng, S., Wang, X., Fu, J., Hu, X., Xiao, X., Huang, L., Zhou, Y., and Zhong, H. (2012) Desalting of phosphopeptides by tandem polypyrrole-c18 reverse phase micropipette tip (TMTip(PPY-C18)) based on hybrid electrostatic, - stacking and hydrophobic interactions for mass spectrometric analysis. Analytica chimica acta. 724:73-79
- Lai, K., Amsterdam, A., Farrington, S., Bronson, R.T., Hopkins, N., and Lees, J.A. (2009) Many ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(1):76-85
- Uechi, T., Nakajima, Y., Nakao, A., Torihara, H., Chakraborty, A., Inoue, K., and Kenmochi, N. (2006) Ribosomal protein gene knockdown causes developmental defects in zebrafish. PLoS One. 1(1):e37
- Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
- Amsterdam, A., Sadler, K.C., Lai, K., Farrington, S., Bronson, R.T., Lees, J.A., and Hopkins, N. (2004) Many ribosomal protein genes are cancer genes in zebrafish. PLoS Biology. 2(5):E139
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