ZFIN is now using GRCz12tu for Genomic Data
Gene
dhx16
- ID
- ZDB-GENE-030131-8589
- Name
- DEAH (Asp-Glu-Ala-His) box polypeptide 16
- Symbol
- dhx16 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA binding activity and helicase activity. Acts upstream of or within endodermal cell differentiation. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of spliceosomal complex. Orthologous to human DHX16 (DEAH-box helicase 16).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55590 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neuromuscular disease and ocular or auditory anomalies with or without seizures | 618733 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR002464 | DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR007502 | Helicase-associated domain |
| Domain | IPR011545 | DEAD/DEAH box helicase domain |
| Domain | IPR011709 | DEAD-box helicase, OB fold |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR048333 | Helicase associated domain (HA2), winged-helix domain |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | DEAD-box helicase, OB fold | DEAD/DEAH box helicase domain | DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site | Helicase-associated domain | Helicase associated domain (HA2), winged-helix domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZVV8 | InterPro | 1054 | ||||||||
| UniProtKB:A0AB32T3V6 | InterPro | 739 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers