Gene
tmsb4x
- ID
- ZDB-GENE-030131-8304
- Name
- thymosin beta 4 X-linked
- Symbol
- tmsb4x Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable actin monomer binding activity and protein sequestering activity. Acts upstream of or within heart development and pronephros development. Predicted to be located in cytoplasm and cytoskeleton. Is expressed in heart; heart rudiment; heart tube; and lateral plate mesoderm. Orthologous to human TMSB4X (thymosin beta 4 X-linked) and TMSB4Y (thymosin beta 4 Y-linked).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-tmsb4x | Song et al., 2024 | |
| MO1-tmsb4x | N/A | Shin et al., 2014 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Beta-thymosin | Beta-thymosin superfamily |
|---|---|---|---|---|
| UniProtKB:Q45QT2 | InterPro | 44 |
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- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmsb4x-201
(1)
|
Ensembl | 677 nt | ||
| mRNA |
tmsb4x-202
(1)
|
Ensembl | 369 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Encodes | EST | fb08c07 | ||
| Encodes | EST | fj40h03 | ||
| Encodes | cDNA | MGC:195143 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:195154 | ZFIN Curated Data | |
| Has Artifact | EST | fa92d06 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001130697 (1) | 682 nt | ||
| Genomic | GenBank:CU914164 (1) | 141464 nt | ||
| Polypeptide | UniProtKB:Q45QT2 (1) | 44 aa |