Gene
tsc22d1
- ID
- ZDB-GENE-030131-7785
- Name
- TSC22 domain family, member 1
- Symbol
- tsc22d1 Nomenclature History
- Previous Names
-
- fj34d05
- wu:fj34d05
- zgc:65869
- zgc:85857
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to be involved in negative regulation of apoptotic process and positive regulation of cell population proliferation. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including forerunner cell group; mucus secreting cell; nervous system; pronephric mesoderm; and pronephros. Orthologous to human TSC22D1 (TSC22 domain family member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85857 (17 images)
- IMAGE:7165302 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | TSC22/Bun | TSC22/Bun, conserved site |
|---|---|---|---|---|
| UniProtKB:Q7SZP1 | InterPro | 145 | ||
| UniProtKB:A0A8M1P8T9 | InterPro | 971 | ||
| UniProtKB:B0V1G3 | InterPro | 133 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tsc22d1-201
(1)
|
Ensembl | 2,896 nt | ||
| mRNA |
tsc22d1-202
(1)
|
Ensembl | 827 nt | ||
| mRNA |
tsc22d1-203
(1)
|
Ensembl | 1,688 nt | ||
| mRNA |
tsc22d1-204
(1)
|
Ensembl | 1,059 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-161H23 | ZFIN Curated Data | |
| Encodes | EST | fj34d05 | ||
| Encodes | EST | IMAGE:7165302 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:65869 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:85857 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001328125 (1) | 4646 nt | ||
| Genomic | GenBank:CR847884 (2) | 157311 nt | ||
| Polypeptide | UniProtKB:A0A8M1P8T9 (1) | 971 aa |
- England, S.J., Campbell, P.C., Banerjee, S., Bates, R.L., Grieb, G., Fancher, W.F., Lewis, K.E. (2024) Transcriptional regulators with broad expression in the zebrafish spinal cord. Developmental Dynamics : an official publication of the American Association of Anatomists. 253(11):1036-1055
- Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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