ficd

ID

ZDB-GENE-030131-6588

Name

FIC domain protein adenylyltransferase

Symbol

ficd Nomenclature History

Previous Names

fk44h08
si:ch211-191d15.5
wu:fk44h08 (1)
zgc:110336

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable AMPylase activity. Predicted to be involved in protein adenylylation and regulation of IRE1-mediated unfolded protein response. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 92. Orthologous to human FICD (FIC domain protein adenylyltransferase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:110336 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ficd Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hereditary spastic paraplegia 92	Alliance	Spastic paraplegia 92, autosomal recessive	620911

Associated With ficd Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003812	Fido domain
Family	IPR040198	Fido domain-containing protein
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Homologous_superfamily	IPR036597	Fido-like domain superfamily
Repeat	IPR019734	Tetratricopeptide repeat