Gene
lamb2l
- ID
- ZDB-GENE-030131-4205
- Name
- laminin, beta 2-like
- Symbol
- lamb2l Nomenclature History
- Previous Names
-
- fc83a09
- si:dkey-32e6.1
- wu:fc83a09 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to be involved in several processes, including axon guidance; basement membrane assembly; and substrate adhesion-dependent cell spreading. Predicted to act upstream of or within cell adhesion. Predicted to be located in basement membrane and extracellular region. Predicted to be part of laminin complex. Is expressed in several structures, including head; nervous system; neural tube; otic vesicle; and pronephric duct.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like domain | Laminin IV type B | Laminin/Netrin Extracellular Matrix | Laminin, N-terminal | Laminin-type EGF domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PDX2 | InterPro | 1836 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lamb2l-201
(1)
|
Ensembl | 5,511 nt | ||
| mRNA |
lamb2l-202
(1)
|
Ensembl | 6,896 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-32E6 | ZFIN Curated Data | |
| Contained in | BAC | RP71-17I16 | ZFIN Curated Data | |
| Encodes | EST | fc83a09 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_021473631 (1) | 6202 nt | ||
| Genomic | GenBank:AL953864 (1) | 249608 nt | ||
| Polypeptide | UniProtKB:A0A8M9PDX2 (1) | 1836 aa |
No data available
- Hu, T., Liu, L., Wang, H., Yang, M., Xu, B., Xie, H., Lin, Z., Jin, X., Wang, P., Liu, Y., Sun, H., Liu, S. (2024) RCAN family member 3 deficiency contributes to noncompaction of the ventricular myocardium. Journal of genetics and genomics = Yi chuan xue bao. 51(5):543-553
- Zhao, N., Wang, X., Wang, T., Xu, X., Liu, Q., Li, J. (2022) Genome-Wide Identification of Laminin Family Related to Follicular Pseudoplacenta Development in Black Rockfish (Sebastes schlegelii). International Journal of Molecular Sciences. 23(18)
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Nagendran, M., Arora, P., Gori, P., Mulay, A., Ray, S., Jacob, T., Sonawane, M. (2015) Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages. Development (Cambridge, England). 142(2):320-30
- Kessels, M.Y., Huitema, L.F., Boeren, S., Kranenbarg, S., Schulte-Merker, S., van Leeuwen, J.L., de Vries, S.C. (2014) Proteomics analysis of the zebrafish skeletal extracellular matrix. PLoS One. 9:e90568
- Sztal, T., Berger, S., Currie, P.D., and Hall, T.E. (2011) Characterization of the laminin gene family and evolution in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(2):422-431
- Jacoby, A.S., Busch-Nentwich, E., Bryson-Richardson, R.J., Hall, T.E., Berger, J., Berger, S., Sonntag, C., Sachs, C., Geisler, R., Stemple, D.L., and Currie, P.D. (2009) The zebrafish dystrophic mutant softy maintains muscle fibre viability despite basement membrane rupture and muscle detachment. Development (Cambridge, England). 136(19):3367-3376
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