Gene

magt1

ID
ZDB-GENE-030131-3667
Name
magnesium transporter 1
Symbol
magt1 Nomenclature History
Previous Names
  • fc49b02
  • wu:fc49b02
  • zgc:56218 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Acts upstream of or within magnesium ion transport. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. Predicted to be part of oligosaccharyltransferase complex. Human ortholog(s) of this gene implicated in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia and congenital disorder of glycosylation Icc. Orthologous to human MAGT1 (magnesium transporter 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
ct104aGtTransgenic insertionUnknownUnknownDNA
sa31974Allele with one point mutationUnknownPremature StopENU
1 - 2 of 2
Show
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-magt1N/AZhou et al., 2009
MO2-magt1N/AZhou et al., 2009
1 - 2 of 2
Show
Human Disease
Associated With magt1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital disorder of glycosylation Icc Alliance Congenital disorder of glycosylation, type Icc 301031
X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia Alliance Immunodeficiency, X-linked, with magnesium defect, Epstein-Barr virus infection and neoplasia 300853
1 - 2 of 2
Associated With magt1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR021149 Oligosaccharyl transferase complex, subunit OST3/OST6
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
1 - 2 of 2
Domain Details Per Protein
Protein Additional Resources Length Oligosaccharyl transferase complex, subunit OST3/OST6 Thioredoxin-like superfamily
UniProtKB:Q7ZV50 InterPro 328
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 14
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA magt1-201 (1) Ensembl 1,639 nt
mRNA magt1-203 (1) Ensembl 531 nt
ncRNA magt1-004 (1) Ensembl 801 nt
ncRNA magt1-005 (1) Ensembl 481 nt
1 - 4 of 4
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-125C23ZFIN Curated Data
EncodesESTfc49b02
EncodescDNAMGC:56218ZFIN Curated Data
1 - 3 of 3
Show
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanMAGT1X
Amino acid sequence comparison (1)
MouseMagt1X
Amino acid sequence comparison (1)
Citations
1 - 4 of 4
Show