Gene

rpl3

ID
ZDB-GENE-030131-1291
Name
ribosomal protein L3
Symbol
rpl3 Nomenclature History
Previous Names
  • wu:fa99g02
  • wu:fb65e09
  • zgc:110350
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within exocrine pancreas development. Predicted to be located in cytoplasm; nucleolus; and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in eye; liver; and pancreas. Used to study Shwachman-Diamond syndrome. Orthologous to human RPL3 (ribosomal protein L3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
hi2437TgTransgenic insertionIntron 2UnknownDNA
sa16344Allele with one point mutationUnknownPremature StopENU
sa20025Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-rpl3N/AProvost et al., 2012
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Human Disease
Associated With rpl3 Human Ortholog
No data available
Associated With rpl3 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019926 Large ribosomal subunit protein uL3, conserved site
Family IPR000597 Large ribosomal subunit protein uL3
Family IPR045077 Large ribosomal subunit protein uL3, archaeal/eukaryotic-type
Homologous_superfamily IPR009000 Translation protein, beta-barrel domain superfamily
Homologous_superfamily IPR044892 Ribosomal protein L3, domain 3, archaeal-type superfamily
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Domain Details Per Protein
Protein Additional Resources Length Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL3, archaeal/eukaryotic-type Large ribosomal subunit protein uL3, conserved site Ribosomal protein L3, domain 3, archaeal-type superfamily Translation protein, beta-barrel domain superfamily
UniProtKB:Q6Q418 InterPro 403
UniProtKB:A0A2R8Q924 InterPro PDB 403
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 3
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rpl3-201 (1) Ensembl 1,382 nt
mRNA rpl3-202 (1) Ensembl 738 nt
mRNA rpl3-204 (1) Ensembl 1,212 nt
ncRNA rpl3-002 (1) Ensembl 801 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-151M15ZFIN Curated Data
EncodesESTfa99g02ZFIN Curated Data
EncodesESTfb65e09
EncodescDNAMGC:110350ZFIN Curated Data
EncodescDNAMGC:191959ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanRPL322
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
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