Gene
suclg2
- ID
- ZDB-GENE-030114-3
- Name
- succinate-CoA ligase GDP-forming subunit beta
- Symbol
- suclg2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable magnesium ion binding activity; purine ribonucleoside triphosphate binding activity; and succinate-CoA ligase activity. Predicted to be involved in tricarboxylic acid cycle. Predicted to act upstream of or within succinyl-CoA metabolic process. Predicted to be located in mitochondrion. Is expressed in lens; liver; pronephric duct; solid lens vesicle; and yolk syncytial layer. Orthologous to human SUCLG2 (succinate-CoA ligase GDP-forming subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb625 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017866 | Succinyl-CoA synthetase, beta subunit, conserved site |
| Domain | IPR005811 | ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain |
| Domain | IPR013650 | ATP-grasp fold, succinyl-CoA synthetase-type |
| Family | IPR005809 | Succinate--CoA ligase-like, beta subunit |
| Family | IPR034722 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial |
| Homologous_superfamily | IPR013815 | ATP-grasp fold, subdomain 1 |
| Homologous_superfamily | IPR016102 | Succinyl-CoA synthetase-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain | ATP-grasp fold, subdomain 1 | ATP-grasp fold, succinyl-CoA synthetase-type | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial | Succinate--CoA ligase-like, beta subunit | Succinyl-CoA synthetase, beta subunit, conserved site | Succinyl-CoA synthetase-like |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1QKY6 | InterPro | 432 | |||||||
| UniProtKB:F1R7X5 | InterPro | 432 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
suclg2-201
(1)
|
Ensembl | 2,390 nt |
Interactions and Pathways
No data available
Plasmids
No data available