Gene
ompb
- ID
- ZDB-GENE-030103-1
- Name
- olfactory marker protein b
- Symbol
- ompb Nomenclature History
- Previous Names
-
- OMP1 (1)
- omp
- zgc:101697
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within sensory perception of smell and signal transduction. Is expressed in olfactory system and sensory neurons. Orthologous to human OMP (olfactory marker protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 30 figures from 18 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101697 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Olfactory marker protein | Olfactory marker superfamily |
|---|---|---|---|---|
| UniProtKB:Q8QGH5 | InterPro | 155 |
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Interactions and Pathways
No data available
Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(-2.0ompb:GAL4) |
|
| 1 | (10) | |
| Tg(-2.0ompb:GAP-CFP) |
|
| 1 | (11) | |
| Tg(-2.0ompb:GAP-YFP) |
|
| 1 | (13) | |
| Tg(-2.0ompb:LY-mRFP) |
|
| 1 | (23) | |
| Tg(-2ompb:Cr.Cop4-YFP) |
|
| 1 | (5) | |
| Tg(-6.0ompb:GAP-YFP) |
|
| 1 | (6) | |
| Tg(-6.0ompb:GFP) |
|
| 1 | (8) | |
| Tg(ompb:ChR2-Kaede-UTR-ompb) |
|
| 1 | Jeong et al., 2021 | |
| Tg(ompb:GAL4) |
|
| 1 | (5) | |
| Tg(ompb:GAL4FF) |
|
| 1 | (6) |
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| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-163I6 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:101697 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_173281 (1) | 1107 nt | ||
| Genomic | GenBank:BX470072 (2) | 211164 nt | ||
| Polypeptide | UniProtKB:Q8QGH5 (1) | 155 aa |
- Rayamajhi, D., Ege, M., Ukhanov, K., Ringers, C., Zhang, Y., Jung, I., D'Gama, P.P., Li, S.S., Cosacak, M.I., Kizil, C., Park, H.C., Yaksi, E., Martens, J.R., Brody, S.L., Jurisch-Yaksi, N., Roy, S. (2024) The forkhead transcription factor Foxj1 controls vertebrate olfactory cilia biogenesis and sensory neuron differentiation. PLoS Biology. 22:e3002468e3002468
- Xue, S., Ly, T.T.N., Vijayakar, R.S., Chen, J., Ng, J., Mathuru, A.S., Magdinier, F., Reversade, B. (2022) HOX epimutations driven by maternal SMCHD1/LRIF1 haploinsufficiency trigger homeotic transformations in genetically wildtype offspring. Nature communications. 13:3583
- Zhu, H., Zhang, X., Xu, S., Wu, J., Hou, M., Zhao, H., Zhou, Q., Zhong, X. (2022) Gene duplication, conservation, and divergence of activating transcription factor 5 gene in zebrafish. Journal of experimental zoology. Part B, Molecular and developmental evolution. 338(5):301-313
- Jeong, Y.M., Choi, T.I., Hwang, K.S., Lee, J.S., Gerlai, R., Kim, C.H. (2021) Optogenetic Manipulation of Olfactory Responses in Transgenic Zebrafish: A Neurobiological and Behavioral Study. International Journal of Molecular Sciences. 22(13):
- Lan, X.R., Li, Y.W., Chen, Q.L., Shen, Y.J., Liu, Z.H. (2020) Tributyltin impaired spermatogenesis and reproductive behavior in male zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 224:105503
- Volz, S.N., Hausen, J., Nachev, M., Ottermanns, R., Schiwy, S., Hollert, H. (2020) Short exposure to cadmium disrupts the olfactory system of zebrafish (Danio rerio) - Relating altered gene expression in the olfactory organ to behavioral deficits. Aquatic toxicology (Amsterdam, Netherlands). 226:105555
- Messina, A., Pulli, K., Santini, S., Acierno, J., Känsäkoski, J., Cassatella, D., Xu, C., Casoni, F., Malone, S.A., Ternier, G., Conte, D., Sidis, Y., Tommiska, J., Vaaralahti, K., Dwyer, A., Gothilf, Y., Merlo, G.R., Santoni, F., Niederländer, N.J., Giacobini, P., Raivio, T., Pitteloud, N. (2019) Neuron-Derived Neurotrophic Factor Is Mutated in Congenital Hypogonadotropic Hypogonadism. American journal of human genetics. 106(1):58-70
- Ahuja, G., Reichel, V., Kowatschew, D., Syed, A.S., Kotagiri, A.K., Oka, Y., Weth, F., Korsching, S.I. (2018) Overlapping but distinct topology for zebrafish V2R-like olfactory receptors reminiscent of odorant receptor spatial expression zones. BMC Genomics. 19:383
- Bergboer, J.G.M., Wyatt, C., Austin-Tse, C., Yaksi, E., Drummond, I.A. (2018) Assaying sensory ciliopathies using calcium biosensor expression in zebrafish ciliated olfactory neurons. Cilia. 7:2
- Bayramli, X., Kocagöz, Y., Sakizli, U., Fuss, S.H. (2017) Patterned Arrangements of Olfactory Receptor Gene Expression in Zebrafish are Established by Radial Movement of Specified Olfactory Sensory Neurons. Scientific Reports. 7:5572
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