Gene

il17rd

ID
ZDB-GENE-020320-5
Name
interleukin 17 receptor D
Symbol
il17rd Nomenclature History
Previous Names
  • sef (1)
  • cb208 (1)
  • id:ibd2875
  • id:ibd5059 (1)
  • zgc:136328
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable interleukin-17 receptor activity. Acts upstream of or within dorsal/ventral pattern formation; negative regulation of MAPK cascade; and negative regulation of fibroblast growth factor receptor signaling pathway. Predicted to be located in membrane. Is expressed in several structures, including digestive system; mesoderm; nervous system; neural keel; and neural rod. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 18 with or without anosmia. Orthologous to human IL17RD (interleukin 17 receptor D).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
40 figures from 26 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Aman et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la010872TgTransgenic insertionUnknownUnknownDNA
la010996TgTransgenic insertionUnknownUnknownDNA
la012050TgTransgenic insertionUnknownUnknownDNA
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-il17rdN/A (3)
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Human Disease
Associated With il17rd Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypogonadotropic hypogonadism 18 with or without anosmia Alliance Hypogonadotropic hypogonadism 18 with or without anosmia 615267
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Associated With il17rd Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013568 SEFIR domain
Domain IPR031951 Interleukin 17 receptor D, N-terminal
Family IPR039465 Interleukin-17 receptor-like
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Domain Details Per Protein
Protein Additional Resources Length Interleukin 17 receptor D, N-terminal Interleukin-17 receptor-like SEFIR domain
UniProtKB:A0A8M1PDW3 InterPro 745
UniProtKB:B3DKQ2 InterPro 744
UniProtKB:Q8QHJ9 InterPro 745
UniProtKB:A0A8M1P417 InterPro 742
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 11
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA il17rd-201 (1) Ensembl 2,984 nt
mRNA il17rd-202 (1) Ensembl 6,340 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-174E22ZFIN Curated Data
EncodesESTcb208 (2)
EncodesESTibd2875
EncodesESTibd5059ZFIN Curated Data
EncodescDNAMGC:136328ZFIN Curated Data
EncodescDNAMGC:195368ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanIL17RD3
Amino acid sequence comparison (3)
Conserved genome location (synteny) (2)
MouseIl17rd14
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
Citations
1 - 10 of 51
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