Gene

meis1a

ID
ZDB-GENE-020122-3
Name
Meis homeobox 1 a
Symbol
meis1a Nomenclature History
Previous Names
  • meis4.1a
  • meis4.1b
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific. Acts upstream of or within brain development. Predicted to be located in nucleus. Is expressed in several structures, including digestive system; nervous system; pectoral fin bud; pectoral fin musculature; and segmental plate. Orthologous to human MEIS1 (Meis homeobox 1).
Genome Resources
Note
meis4.1b was merged into meis4.1a because they were splice variants of the same gene according to the original publication by Waskiewicz et al., 2001.
Comparative Information
Expression
All Expression Data
10 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
iem1Allele with one delinsDonor Splice SiteUnknownCRISPR
la021291TgTransgenic insertionUnknownUnknownDNA
la028180TgTransgenic insertionUnknownUnknownDNA
sa16771Allele with one point mutationUnknownSplice SiteENU
sa25673Allele with one point mutationUnknownSplice SiteENU
sa44514Allele with one point mutationUnknownUnknownENU
sa45085Allele with one point mutationUnknownPremature StopENU
zko1001aAllele with one deletionUnknownUnknownCRISPR
zko1001bAllele with one deletionUnknownUnknownCRISPR
1 - 9 of 9
Show
Sequence Targeting Reagents
1 - 7 of 7
Show
Human Disease
Associated With meis1a Human Ortholog
No data available
Associated With meis1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001356 Homeodomain
Domain IPR008422 KN homeodomain
Domain IPR032453 Homeobox protein PKNOX/Meis, N-terminal
Family IPR050224 Three Amino acid Loop Extension (TALE) homeobox
Homologous_superfamily IPR009057 Homedomain-like superfamily
1 - 5 of 5
Domain Details Per Protein
Protein Additional Resources Length Homedomain-like superfamily Homeobox protein PKNOX/Meis, N-terminal Homeodomain KN homeodomain Three Amino acid Loop Extension (TALE) homeobox
UniProtKB:A0A8M2B7B4 InterPro 379
UniProtKB:Q7SZP3 InterPro 380
1 - 2 of 2
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 1
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA meis1a-201 (1) Ensembl 2,185 nt
mRNA meis1a-203 (1) Ensembl 760 nt
mRNA meis1a-204 (1) Ensembl 942 nt
ncRNA meis1a-003 (1) Ensembl 933 nt
1 - 4 of 4
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-212H16ZFIN Curated Data
Contained inBACDKEY-202B17ZFIN Curated Data
EncodescDNAMGC:65739ZFIN Curated Data
EncodescDNAMGC:76814ZFIN Curated Data
1 - 4 of 4
Show
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanMEIS12
Conserved genome location (synteny) (1)
Functional complementation (1)
Citations
1 - 10 of 17
Show