Gene
cldn3d
- ID
- ZDB-GENE-010328-3
- Name
- claudin 3d
- Symbol
- cldn3d Nomenclature History
- Previous Names
-
- cldnc (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable structural molecule activity. Acts upstream of or within fin regeneration. Predicted to be located in anchoring junction and membrane. Predicted to be active in bicellular tight junction and plasma membrane. Is expressed in digestive system; heart; intestinal bulb primordium; pleuroperitoneal region; and pronephric mesoderm. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 116. Orthologous to several human genes including CLDN3 (claudin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77581 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Claudin | Claudin-3 | PMP-22/EMP/MP20/Claudin |
---|---|---|---|---|---|
UniProtKB:Q90XR2 | InterPro | 218 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-54M16 | ZFIN Curated Data | |
Encodes | cDNA | MGC:77581 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_131764 (1) | 1863 nt | ||
Genomic | GenBank:CR847847 (2) | 76887 nt | ||
Polypeptide | UniProtKB:Q90XR2 (1) | 218 aa |
No data available
- Liu, Y., Kassack, M.E., McFaul, M.E., Christensen, L.N., Siebert, S., Wyatt, S.R., Kamei, C.N., Horst, S., Arroyo, N., Drummond, I.A., Juliano, C.E., Draper, B.W. (2022) Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary. eLIFE. 11:
- Lukowicz-Bedford, R.M., Farnsworth, D.R., Miller, A.C. (2022) Connexinplexity: The spatial and temporal expression of connexin genes during vertebrate organogenesis. G3 (Bethesda). 12(5):
- Luo, T., Wang, X., Jin, Y. (2021) Low concentrations of imidacloprid exposure induced gut toxicity in adult zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 241:108972
- Metikala, S., Casie Chetty, S., Sumanas, S. (2021) Single-cell transcriptome analysis of the zebrafish embryonic trunk. PLoS One. 16:e0254024
- Phatak, M., Kulkarni, S., Miles, L.B., Anjum, N., Dworkin, S., Sonawane, M. (2021) Grhl3 promotes retention of epidermal cells under endocytic stress to maintain epidermal architecture in zebrafish. PLoS Genetics. 17:e1009823
- Solis, C.J., Hamilton, M.K., Caruffo, M., Garcia-Lopez, J.P., Navarrete, P., Guillemin, K., Feijoo, C.G. (2020) Intestinal Inflammation Induced by Soybean Meal Ingestion Increases Intestinal Permeability and Neutrophil Turnover Independently of Microbiota in Zebrafish. Frontiers in immunology. 11:1330
- Bruch-Bertani, J.P., Uribe-Cruz, C., Pasqualotto, A., Longo, L., Ayres, R., Bortolin Beskow, C., Luis Barth, A., Lima-Morales, D., Meurer, F., Tayguara, G., Guerreiro, S., da Silveira, T.R., Álvares-da-Silva, M.R., Dall'Alba, V. (2019) Hepatoprotective Effect of Probiotic Lactobacillus rhamnosus GG Through the Modulation of Gut Permeability and Inflammasomes in a Model of Alcoholic Liver Disease in Zebrafish. Journal of the American College of Nutrition. 39(2):163-170
- Wu, N., Xu, X., Wang, B., Li, X.M., Cheng, Y.Y., Li, M., Xia, X.Q., Zhang, Y.A. (2019) Anti-foodborne enteritis effect of galantamine potentially via acetylcholine anti-inflammatory pathway in fish. Fish & shellfish immunology. 97:204-215
- Guo, X., Li, J., Ran, C., Wang, A., Xie, M., Xie, Y., Ding, Q., Zhang, Z., Yang, Y., Zhou, Z. (2018) Dietary nucleotides can directly stimulate the immunity of zebrafish independent of the intestinal microbiota. Fish & shellfish immunology. 86:1064-1071
- Khatib, A.M., Lahlil, R., Hagedorn, M., Delomenie, C., Christophe, O., Denis, C., Siegfried, G. (2016) Biological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis. Oncotarget. 7(11):12102-20
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