Gene
hspe1
- ID
- ZDB-GENE-000906-2
- Name
- heat shock 10 protein 1
- Symbol
- hspe1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be active in mitochondrial matrix. Is expressed in several structures, including alar plate midbrain region; digestive system; midbrain; pectoral fin; and segmental plate. Orthologous to human HSPE1 (heat shock protein family E (Hsp10) member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6898979 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Pei et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
hg76 | Allele with one deletion | Unknown | Unknown | CRISPR | |
hg77 | Allele with one deletion | Unknown | Unknown | CRISPR | |
la026912Tg | Transgenic insertion | Unknown | Unknown | DNA | |
la026913Tg | Transgenic insertion | Unknown | Unknown | DNA |
1 - 4 of 4
Show
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | GroES chaperonin family | GroES chaperonin superfamily | GroES-like superfamily |
---|---|---|---|---|---|
UniProtKB:F6NVJ1 | InterPro | 99 | |||
UniProtKB:Q6IQI7 | InterPro | 100 |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-83M22 | ZFIN Curated Data | |
Encodes | EST | IMAGE:6898979 | Thisse et al., 2004 | |
Encodes | cDNA | MGC:86747 | ZFIN Curated Data |
1 - 3 of 3
Show
Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001328390 (1) | 1213 nt | ||
Genomic | GenBank:BX530407 (1) | 292409 nt | ||
Polypeptide | UniProtKB:Q6IQI7 (1) | 100 aa |
- Rehman, S.U., Nadeem, A., Javed, M., Hassan, F.U., Luo, X., Khalid, R.B., Liu, Q. (2020) Genomic Identification, Evolution and Sequence Analysis of the Heat-Shock Protein Gene Family in Buffalo. Genes. 11(11):
- Pei, W., Xu, L., Huang, S.C., Pettie, K., Idol, J., Rissone, A., Jimenez, E., Sinclair, J.W., Slevin, C., Varshney, G.K., Jones, M., Carrington, B., Bishop, K., Huang, H., Sood, R., Lin, S., Burgess, S.M. (2018) Guided genetic screen to identify genes essential in the regeneration of hair cells and other tissues. NPJ Regenerative medicine. 3:11
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Li, J.T., Hou, G.Y., Kong, X.F., Li, C.Y., Zeng, J.M., Li, H.D., Xiao, G.B., Li, X.M., Sun, X.W. (2015) The fate of recent duplicated genes following a fourth-round whole genome duplication in a tetraploid fish, common carp (Cyprinus carpio). Scientific Reports. 5:8199
- Varshney, G.K., Pei, W., LaFave, M.C., Idol, J., Xu, L., Gallardo, V., Carrington, B., Bishop, K., Jones, M., Li, M., Harper, U., Huang, S.C., Prakash, A., Chen, W., Sood, R., Ledin, J., Burgess, S.M. (2015) High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9. Genome research. 25(7):1030-42
- Liu, C., Xu, H., Lam, S.H., and Gong, Z. (2013) Selection of Reliable Biomarkers from PCR Array Analyses Using Relative Distance Computational Model: Methodology and Proof-of-Concept Study. PLoS One. 8(12):e83954
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Jin, Y., Zhang, X., Lu, D., and Fu, Z. (2012) Proteomic Analysis of Hepatic Tissue in Adult Female Zebrafish (Danio rerio) Exposed to Atrazine. Archives of environmental contamination and toxicology. 62(1):127-34
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
1 - 10 of 13
Show