Gene

hoxc11b

ID
ZDB-GENE-000822-3
Name
homeobox C11b
Symbol
hoxc11b Nomenclature History
Previous Names
  • Hoxa11
  • im:7165141
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in embryonic skeletal joint morphogenesis and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in caudal fin; pleuroperitoneal region; presumptive telencephalon; pronephric mesoderm; and tail bud. Orthologous to human HOXC11 (homeobox C11).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
17 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa35003Allele with one point mutationUnknownPremature StopENU
sud124bAllele with one deletionExon 1UnknownCRISPR
sud128Allele with one delinsExon 1UnknownCRISPR
sud162aAllele with one deletionExon 1UnknownCRISPR
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-hoxc11b (2)
MO1-hoxc11bN/ASundaramoorthi et al., 2023
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Human Disease
Associated With hoxc11b Human Ortholog
No data available
Associated With hoxc11b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR020479 Homeodomain, metazoa
Domain IPR021918 Domain of unknown function DUF3528, homeobox protein, eukaryotic
Homologous_superfamily IPR009057 Homedomain-like superfamily
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Domain Details Per Protein
Protein Additional Resources Length Domain of unknown function DUF3528, homeobox protein, eukaryotic Homedomain-like superfamily Homeobox, conserved site Homeodomain Homeodomain, metazoa
UniProtKB:A0A0R4IDM3 InterPro 306
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 11
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hoxc11b-201 (1) Ensembl 2,649 nt
mRNA hoxc11b-202 (1) Ensembl 4,372 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
EncodesESTeu752Thisse et al., 2005
EncodesESTIMAGE:7165141Thisse et al., 2004
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanHOXC1112
Amino acid sequence comparison (1)
Conserved genome location (synteny) (2)
MouseHoxc1115
Nucleotide sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
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