Gene
crestin
- ID
- ZDB-GENE-000208-13
- Name
- crestin
- Symbol
- crestin Nomenclature History
- Previous Names
-
- ctn (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Is expressed in several structures, including ectomesenchyme; embryonic structure; head; nervous system; and neural crest.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 173 figures from 113 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein | Additional Resources | Length |
---|---|---|
UniProtKB:A0A1D5NSV4 | InterPro | 593 |
1 - 1 of 1
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
crestin-201
(1)
|
Ensembl | 4,437 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
---|---|---|---|---|---|
Tg(-1.2crestin:EGFP) |
|
| 1 | Jang et al., 2021 | |
Tg(-1crestin:GAL4-VP16,14xUAS-E1B:EGFP) |
|
| 1 | (5) | |
Tg2(crestin:EGFP) |
|
| 1 | (2) | |
Tg(-4.5-crestin:EGFP) |
|
| 1 | (5) | |
Tg(-4.5-crestin:mCherry) |
|
| 1 | (6) | |
Tg(crestin:Cre-ERT2,cryaa:YFP) |
|
| 1 | (2) | |
Tg(crestin:EGFP) |
|
| 1 | (6) | |
Tg(crestin:mCherry) |
|
| 2 | (2) |
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Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-261D9 | ZFIN Curated Data |
1 - 1 of 1
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_130993 (1) | 4437 nt | ||
Genomic | GenBank:CR450840 (2) | 194617 nt | ||
Polypeptide | UniProtKB:A0A1D5NSV4 (1) | 593 aa |
No data available
- Xia, X., Song, W., Zhang, F., Fan, Y., Zhang, B., Chen, X. (2025) ctdsp2 Knockout Induces Zebrafish Craniofacial Dysplasia via p53 Signaling Activation. International Journal of Molecular Sciences. 26:
- Ibarra-García-Padilla, R., Nambiar, A., Hamre, T.A., Singleton, E.W., Uribe, R.A. (2024) Expansion of a neural crest gene signature following ectopic MYCN expression in sympathoadrenal lineage cells in vivo. PLoS One. 19:e0310727e0310727
- Moore, J.A., Moreno-Campos, R., Noah, A.S., Singleton, E.W., Uribe, R.A. (2024) BMP signaling pathway member expression is enriched in enteric neural progenitors and required for zebrafish enteric nervous system development. Developmental Dynamics : an official publication of the American Association of Anatomists. :
- Niu, X., Zhang, F., Gu, W., Zhang, B., Chen, X. (2024) FBLN2 is associated with Goldenhar syndrome and is essential for cranial neural crest cell development. Annals of the New York Academy of Sciences. 1537(1):113-128
- Song, W., Xia, X., Fan, Y., Zhang, B., Chen, X. (2024) Functional and Genetic Analyses Unveil the Implication of CDC27 in Hemifacial Microsomia. International Journal of Molecular Sciences. 25(9):
- Sun, L., Ping, L., Fan, X., Fan, Y., Zhang, B., Chen, X. (2024) amer1 Regulates Zebrafish Craniofacial Development by Interacting with the Wnt/β-Catenin Pathway. International Journal of Molecular Sciences. 25(2):
- Tignard, P., Pottin, K., Geeverding, A., Doulazmi, M., Cabrera, M., Fouquet, C., Liffran, M., Fouchard, J., Rosello, M., Albadri, S., Del Bene, F., Trembleau, A., Breau, M.A. (2024) Basement membranes are crucial for proper olfactory placode shape, position and boundary with the brain, and for olfactory axon development. eLIFE. 12:
- Leid, J., Gray, R., Rakita, P., Koenig, A.L., Tripathy, R., Fitzpatrick, J.A.J., Kaufman, C., Solnica-Krezel, L., Lavine, K.J. (2023) Deletion of taf1 and taf5 in zebrafish capitulate cardiac and craniofacial abnormalities associated with TAFopathies through perturbations in metabolism. Biology Open. 12(7):
- Liu, X., Jones, W.D., Quesnel-Vallières, M., Devadiga, S.A., Lorent, K., Valvezan, A.J., Myers, R.L., Li, N., Lengner, C.J., Barash, Y., Pack, M., Klein, P.S. (2023) The Tumor Suppressor Adenomatous Polyposis Coli (apc) Is Required for Neural Crest-Dependent Craniofacial Development in Zebrafish. Journal of developmental biology. 11(3):
- Mao, A., Li, Z., Ning, G., Zhou, Z., Wei, C., Li, J., He, X., Wang, Q. (2023) Sclerotome-derived PDGF signaling functions as a niche cue responsible for primitive erythropoiesis. Development (Cambridge, England). 150(22):
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