ZFIN Fish: AB + CRISPR1-g6pd

Human Disease modelled by AB + CRISPR1-g6pd

Disease	Conditions	Citation
hemolytic anemia	chemical treatment: chloroquine	Hwang et al., 2018
hemolytic anemia	standard conditions	Hwang et al., 2018

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Gene Expression

RNA Expression

No data available

Protein Expression

No data available

Reporter Gene Expression

No data available

Phenotype

Phenotype	Conditions	Figures
blood accumulation pericardial region, abnormal	chemical treatment: chloroquine, chemical treatment: N,N'-[disulfanediyldi(ethane-2,1-diyl)]bis[2-(1H-indol-3-yl)ethan-1-amine]	Fig. 4 from Hwang et al., 2018
glucose-6-phosphate dehydrogenase activity decreased occurrence, abnormal	control	Fig. 4 from Hwang et al., 2018
glucose-6-phosphate dehydrogenase activity decreased occurrence, abnormal	chemical treatment: N,N'-[disulfanediyldi(ethane-2,1-diyl)]bis[2-(1H-indol-3-yl)ethan-1-amine]	Fig. 4 from Hwang et al., 2018
glucose-6-phosphate dehydrogenase activity decreased occurrence, abnormal	chemical treatment: chloroquine	Fig. 4 from Hwang et al., 2018
pericardium edematous, abnormal	control	Fig. 4 from Hwang et al., 2018
pericardium edematous, abnormal	chemical treatment: chloroquine, chemical treatment: N,N'-[disulfanediyldi(ethane-2,1-diyl)]bis[2-(1H-indol-3-yl)ethan-1-amine]	Fig. 4 from Hwang et al., 2018
pericardium edematous, exacerbated	chemical treatment: chloroquine	Fig. 4 from Hwang et al., 2018
whole organism NADPH decreased amount, abnormal	control	Fig. 4 from Hwang et al., 2018
whole organism reactive oxygen species increased amount, abnormal	control	Fig. 4 from Hwang et al., 2018
whole organism reactive oxygen species increased amount, exacerbated	chemical treatment: chloroquine, chemical treatment: N,N'-[disulfanediyldi(ethane-2,1-diyl)]bis[2-(1H-indol-3-yl)ethan-1-amine]	Fig. 4 from Hwang et al., 2018

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Citations

Include unpublished citations

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