ZFIN Fish: pd108Tg

Human Disease model utilizes pd108Tg

No data available

Gene Expression

RNA Expression

Expressed Gene	Structure	Conditions	Figures
cxcl8a	ventricular epicardium	cryoablation: cardiac ventricle	Fig. 5 from El-Sammak et al., 2022
emilin2a	ventricular epicardium	cryoablation: cardiac ventricle	Fig. S3 from El-Sammak et al., 2022
hgfa	pharyngeal arch 3 pharyngeal arch 4 pharyngeal arch 3-7 pharyngeal arch 6 pharyngeal arch 5	standard conditions	2 figures from Isabella et al., 2020
hgfa	pharyngeal arch 3-7	chemical treatment by environment: retinoic acid	Fig. 4 from Isabella et al., 2020
pitx2	prechordal plate	standard conditions	Fig. 1 from Nagelberg et al., 2015
vegfc	ventricular epicardium	control	Fig. 1 from El-Sammak et al., 2022
vegfc	ventricular epicardium	cryoablation: cardiac ventricle	Fig. 1 from El-Sammak et al., 2022

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Protein Expression

Reporter Gene Expression

Phenotype

Citations

Include unpublished citations

Boezio, G.L.M., Zhao, S., Gollin, J., Priya, R., Mansingh, S., Guenther, S., Fukuda, N., Gunawan, F., Stainier, D.Y.R. (2022) The developing epicardium regulates cardiac chamber morphogenesis by promoting cardiomyocyte growth. Disease models & mechanisms. 16(5):
El-Sammak, H., Yang, B., Guenther, S., Chen, W., Marín-Juez, R., Stainier, D.Y.R. (2022) A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration. Circulation research. 130(7):1014-1029
Isabella, A.J., Barsh, G.R., Stonick, J.A., Dubrulle, J., Moens, C.B. (2020) Retinoic Acid Organizes the Zebrafish Vagus Motor Topographic Map via Spatiotemporal Coordination of Hgf/Met Signaling. Developmental Cell. 53(3):344-357.e5
Nagelberg, D., Wang, J., Su, R., Torres-Vazquez, J., Targoff, K.L., Poss, K.D., Knaut, H. (2015) Origin, specification and plasticity of the great vessels of the heart.. Current biology : CB. 25:2099-2110
Wang, J., Cao, J., Dickson, A.L., Poss, K.D. (2015) Epicardial regeneration is guided by cardiac outflow tract and Hedgehog signalling. Nature. 522(7555):226-30

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