CRISPR

CRISPR4-itgav

ID
ZDB-CRISPR-250402-1
Name
CRISPR4-itgav
Previous Names
None
Target
Sequence
5' - CGTGTGCACCTCTCTACCAG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
zf4212 itgav
Expression
Gene expression in Wild Types + CRISPR4-itgav
No data available
Phenotype
Phenotype resulting from CRISPR4-itgav
No data available
Phenotype of all Fish created by or utilizing CRISPR4-itgav
Phenotype Fish Conditions Figures
whole organism decreased weight, abnormal itgavzf4212/zf4212 standard conditions Figure 5. with image from Ghasempour et al., 2024
regulation of transforming growth factor beta receptor signaling pathway disrupted, abnormal itgavzf4212/zf4212 standard conditions Figure 4. with image from Ghasempour et al., 2024
whole organism decreased length, abnormal itgavzf4212/zf4212 standard conditions Figure 5. with image from Ghasempour et al., 2024
brain hemorrhagic, abnormal itgavzf4212/zf4212 standard conditions Figure 4. with image from Ghasempour et al., 2024
mid intestine enteric musculature ab1-smad3 labeling decreased amount, abnormal itgavzf4212/zf4212 standard conditions Figure 5. with image from Ghasempour et al., 2024
mid intestine morphology, abnormal itgavzf4212/zf4212 standard conditions Figure 5. with image from Ghasempour et al., 2024
mid intestine epithelium enterocyte ab1-smad3 labeling decreased amount, abnormal itgavzf4212/zf4212 standard conditions Figure 5. with image from Ghasempour et al., 2024
pericardium edematous, abnormal itgavzf4212/zf4212 standard conditions Figure 4. with image from Ghasempour et al., 2024
microglial cell decreased amount, abnormal itgavzf4212/zf4212 standard conditions Figure 4. with image from Ghasempour et al., 2024
ocular blood vessel decreased branchiness, abnormal itgavzf4212/zf4212 standard conditions Figure 4. with image from Ghasempour et al., 2024
whole organism decreased life span, abnormal itgavzf4212/zf4212 standard conditions Figure 5. with image from Ghasempour et al., 2024
mid intestine epithelium enterocyte Ab6-smad3 labeling decreased amount, abnormal itgavzf4212/zf4212 standard conditions Figure 5. with image from Ghasempour et al., 2024
mid intestine inflamed, abnormal itgavzf4212/zf4212 standard conditions Figure 5. with image from Ghasempour et al., 2024
ocular blood vessel structure, abnormal itgavzf4212/zf4212 standard conditions Figure 4. with image from Ghasempour et al., 2024
Citations
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